Shaping biodegradable polymers as nanostructures: Fabrication and applications.

The interest in micro- and nano-devices based on biodegradable polymers for in vivo applications is growing rapidly and the key to these applications lies in the fashioning of features analogous to the size of cells. This paper presents fabrication techniques for leveraging micro- and nanostructures on biodegradable polymers. Innovative approaches such as replication molding, laser interference lithography, nanosphere lithography, and block copolymer lithography are discussed. These techniques demonstrate excellent potential for fabricating biodegradable polymeric devices in both a laboratory and industry scale.: